Metastatic melanoma in the small intestine: infrequent cause of perforation

case report

Authors

DOI:

https://doi.org/10.31837/cir.urug.7.1.4

Keywords:

small intestine, melanoma, peritonitis, metastasis

Abstract

Introduction: The small intestine is the most frequent site of metastatic melanoma. However, its diagnosis continues to be a challenge since it is usually asymptomatic or with non-specific symptoms.Few cases result in complications, peritonitis due to perforation being infrequent. The objective of the work is to report a clinical case of peritonitis due to perforation of a melanoma metastasis in the small intestine.

Clinical case: A 66-year-old male patient diagnosed with melanoma of the neck and secondary bone, brain and lung melanoma, underwent emergency surgery for acute peritonitis due to perforation of metastasis in the small intestine, which was resected and anastomosed. The histology confirmed the secondary nature of the cutaneous melanoma.

Conclusion: Knowing that the jejunum-ileum is the most frequent site of melanoma metastases, in the presence of non-specific digestive symptoms or anemia, its involvement should be suspected and possible therapeutic alternatives should be evaluated.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Michalinos A, Felekouras E, Athanasiou A, Tsaparas P, Mantas D, Kouraklis G. Melanoma metastases to gastrointestinal tract. Am Surg. 2015;81(5):E212-4. doi: 10.1177/000313481508100510

Kibbi N, Kluger H, Choi JN. Melanoma: Clinical presentations. Cancer Treat Res. 2016;167:107–29. doi: 10.1007/978-3-319-22539-5_4

La Selva D, Kozarek RA, Dorer RK, Rocha FG, Gluck M. Primary and metastatic melanoma of the GI tract: clinical presentation, endoscopic findings, and patient outcomes. Surg Endosc. 2020;34(10):4456–62.: doi: 10.1007/s00464-019-07225-8

Mantas D, Tsaparas P, Charalampoudis P, Gogas H, Kouraklis G. Emergency surgery for metastatic melanoma. Int J Surg Oncol. 2014;2014:987170. doi: 10.1155/2014/987170

Amarillo D, De Boni D, Nantes F, Tambasco C, Brayer C, Palacios C, et al. Melanoma cutáneo en Uruguay: características clínico-epidemiológicas y sobrevida en cohorte de pacientes de dos centros de referencia en el período 2008-2017. Rev Med Urug. 2020;36(2):146-54. doi: 10.29193/RMU.36.2.4

Coit DG, Thompson JA, Albertini MR, Barker C, Carson WE, Contreras C, et al. Cutaneous melanoma, version 2.2019, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2019;17(4):367–402. doi: 10.6004/jnccn.2019.0018.

Bender GN, Maglinte DD, McLarney JH, Rex D, Kelvin FM. Malignant melanoma: patterns of metastasis to the small bowel, reliability of imaging studies, and clinical relevance. Am J Gastroenterol. 2001;96(8):2392–400. doi: 10.1111/j.1572-0241.2001.04041.x.

Lianos GD, Messinis T, Doumos R, Papoudou-Bai A, Bali CD. A patient presenting with acute abdomen due to metastatic small bowel melanoma: a case report. J Med Case Rep. 2013;7:216. doi: 10.1186/1752-1947-7-216.

Ollila DW, Essner R, Wanek LA, Morton DL. Surgical resection for melanoma metastatic to the gastrointestinal tract. Arch Surg. 1996;131(9):975–9;979–80. doi: 10.1001/archsurg.1996.01430210073013.

Brummel N, Awad Z, Frazier S, Liu J, Rangnekar N. Perforation of metastatic melanoma to the small bowel with simultaneous gastrointestinal stromal tumor. World J Gastroenterol. 2005;11(17):2687–9. doi: 10.3748/wjg.v11.i17.2687.

Published

2023-04-28

How to Cite

1.
Romero L, Arcienega P, Telles L, González D. Metastatic melanoma in the small intestine: infrequent cause of perforation: case report. Cir. Urug. [Internet]. 2023 Apr. 28 [cited 2024 May 12];7(1):ecir.urug.7.1.4. Available from: https://revista.scu.org.uy/index.php/cir_urug/article/view/5732

Most read articles by the same author(s)

1 2 3 > >>